I could only find 7 WR's who ran under 4.3 at the NFL combine:
1) 2010 - Jacoby Ford - 4.28 - Selected in the 4th round - Appeared in 38 games over 4 years and never finished higher than WR67; tried to catch on in the CFL but couldn't
2) 2013 - Marquise Goodwin - 4.27 - Selected in the 3rd round - Only finish worth mentioning was WR29 in 2017, no other finish better than WR70 - currently a free agent
3) 2015 - JJ Nelson - 4.28 - Selected in the 5th round - Spent 5 years in the NFL with a best of WR57 in 2016; bounced around practice squads a few years before calling it quits
4) 2017 - John Ross - 4.22 - Selected in the 1st round - Best finish was WR73, has not played since week 14 of 2021; just signed today with the Eagles, 43.4 catch percentage
5) 2020 - Henry Ruggs - 4.27 - Selected in the 1st round - WR89 finish as a rookie, was WR31 thru 7 games in 2021, until he destroyed his career and is currently in prison
6) 2022 - Tyquan Thornton - 4.28 - Selected in the 2nd round - 35 catches/338 yards/2 TD's thru his first 2 injury plagued seasons; currently pretty low on the NE depth chart
7) 2024 - Xavier Worthy - 4.21 - Selected in the 1st round - Can he become the first WR to translate his monster speed into fantasy/NFL success?