I don't see any reason that starting in week 8 CMC isn't seeing 20 touches every week, which is pretty in-line with what he was doing in Carolina in 2022. Factor in that the Panthers couldn't sustain drives at all, so they were running BY FAR the fewest plays of any team in the NFL, and there is upside for more, even with more touch competition. Also, the 49ers are the #12 team in the NFL in rushing yards before contact (were #2 with Trent Williams who is due back this week) Carolina is 26th. For reference's sake, the Rams are dead last. So, chances are CMC's 4.6 YPC goes up quite a bit, likely over 5.1, with more big plays mixed in. Jeff Wilson is at 4.9 right now, so if anything, could be undershooting it.
I think there is a decent argument for Saquon Barkley over CMC, but I'm struggling to find one for any other RB, maybe Taylor if he looks fully healthy, maybe?